Show simple item record

dc.contributor.authorWall, Geoffrey C.
dc.contributor.authorJacoby, Henry I.
dc.identifier.citationAmerican Journal of Pharmaceutical Education, Volume 66, Issue 2, 2002, Pages 148-152en
dc.descriptionGeoffrey C. Wall is an Associate Professor of Pharmacy Practice in the College of Pharmacy and Health Sciences. He can be contacted at geoff.wall@drake.eduen
dc.description.abstractPROLOGUE: Gastroesophageal reflux disease (GERD) is a pathologic condition of injury to the esophagus caused by regurgitation of gastric or gastroduodenal contents into the lumen of the esophagus. Histopathology of the esophageal mucosa may or may not be present. Gastroesophageal reflux of acid and gastric contents often causes a condition commonly referred to as heartburn. This is characterized as a retro-sternal burning sensation that radiates to the throat and interscapular region. It may be confused, even in the emergency room, with anginal pain or the onset of myocardial infarction; therefore its rapid diagnosis is important. In many patients GERD should be considered a chronic and lifelong illness and maintenance therapy is often needed. Repeated exposure of the esophagus to stomach contents leads to esophagitis. In severe cases, this can actually erode esophageal tissue (erosive esophagitis). In the last five to seven years several new treatment options for GERD have become available. These include antise-cretory agents such as the proton pump inhibitors, and new surgical techniques that have improved Nissen fundoplication safety and efficacy rates(3-4). Clinicians caring for patients with this common disorder need to understand the pathology behind GERD, its common (and uncommon) clinical manifestations, and current treatment options as recommended by the American College of Gastroenterology.en
dc.format.extent466652 bytes
dc.publisherAmerican Association of Colleges of Pharmacyen
dc.subjectGastroesophageal reflux.en
dc.subjectGastroesophageal reflux--Diagnosis.en
dc.subjectGastroesophageal reflux--Diet therapy.en
dc.subjectGastroesophageal reflux--Treatmenten
dc.subjectEsophageal sphincter.en
dc.title"Gastroesophageal reflux disease"en

Files in this item


This item appears in the following Collection(s)

  • Pharmacy Practice
    Publications and research submitted by the faculty members of the Department of Pharmacy Practice.

Show simple item record