Now showing items 129-148 of 197

  • Influence of Exogenous PlGF on Apoptosis in the H9c2 Cardiomyoblast Cell Line 

    Alberts, Timothy; Kasinathan, Sivakanthan; Theis, Kaitlin (2010-04-28)
    Placenta growth factor (PlGF) is known to inhibit apoptosis in cells such as trophoblast or endothelial cells. Although PlGF is expressed in heart tissue in vivo and in vitro, little is known about its antiapoptotic effects ...
  • Inhibition of drug efflux by pluronics in S. cerevisiae 

    Diezi, Thomas; Ruggle, Brian; Pandit, Nivedita K.; Sleister, Heidi (2007-05-31)
    Overexpression of P-gp efflux pumps is believed to be responsible for multidrug resistance of mammalian cancer cells. Inhibition of these pumps is expected to increase the efficacy and decrease the toxicity of chemotherapeutic ...
  • Interactions of Miltefosine and Phospholipid DPPC at the Air/Water Interface 

    Wildgen, Sarah M. (2009-04-20)
    Several Langmuir monolayer studies have suggested that the drug Hexadecylphosphocholine (miltefosine) has a mode of action which is directly related to the cell membrane. Because the exact mode of action still unknown, ...
  • "Ion and albumin influence on measurement of metabolic debt" 

    Heck, Amber; Mueller, Dana; Woodard, Meredith; Lewis, Trisha; Waszgis, Michaela; Theisen-Toupal, Jesse; Sanders, Rachel; Matlack, Angela; Buising, Charisse; Henderson, LaRhee; Hopkins, James; Devey, Jennifer; Smoot, Dustin; Wall, Piper (2006-06-07)
    Alterations in Na+, Cl-, and albumin, if present and not accounted for, may lead one to false conclusions concerning perfusion status as indicated by base excess (BEtotal).
  • Ionization of Atomic Hydrogen in Strong Infrared Laser Fields 

    Abeln, Brant; Secor, Ethan; Weflen, Daniel; Grum-Grzhimailo, Alexei (2010-04-19)
    We have used the matrix iteration method of Nurhuda and Faisal (Phys. Rev. A 60 (1999) 3125) to treat ionization of atomic hydrogen by a strong laser pulse. After testing our predictions against a variety of previous ...
  • Ionization Of The Hydrogen Molecular Ion By Ultrashort Intense Elliptically Polarized Laser Radiation 

    DuToit, Ryan (2013-04-17)
    We report results for the single- and multi-photon ionization of the H2 + ion irradiated by ultrashort elliptically polarized laser pulses with central photon energies from the ionization threshold up to 300 eV. Using the ...
  • Isolation of yeast genes that suppress the chromosome loss defect of 'YAC stability in mitosis' mutants. 

    Ruggle, Brian; Rusdianto, Eveline; Sleister, Heidi (2007-05-17)
    The eukaryotic cell cycle and processes that maintain genome stability occur with high fidelity. Mutations in genes important for the structure, replication, repair, and/or segregation of chromosomes are correlated with ...
  • Isolation of Yeast Genes that Suppress the Chromosome Loss Defect of ysm's 22, 77, 83, and 84 

    Carter, Chelsea; Christie, Allen; Dicken, Matthew; Helget, Holly; Hong, Davy; Kim, Yun; Mazurek, Stefan; Michaels, Whitney; Nguyen, Lahn G.; Peterson, Whitney; Swehla, Kendra; Swenson, Jill; Thomas, Maggie; Tolliver, Clare; Wilt, Nicole (2009-04-21)
    Cancer cells display both chromosome rearrangements and abnormal numbers of chromosomes. High fidelity chromosome transmission requires the accuracy of multiple processes such as DNA replication, DNA repair, sister chromatid ...
  • "Issues with hypotensive stabilization following hemorrhage" 

    Matlack, Angela; Byers, Melissa; Scaletta, Amber; Lewis, Trisha; Waszgis, Michaela; Heck, Amber; Henderson, LaRhee; Theisen-Toupal, Jesse; Sanders, Rachel; Hopkins, James; Buising, Charisse; Meinders, Kandis; Wall, Piper (2006-06-07)
    We are investigating pharmacologic interruption of angiotensin II production (enalaprilat) combined with either 7.8% hypertonic saline dextran (HSD) or a hemoglobin based oxygen carrier (HBOC, Oxyglobin) as methods to ...
  • Learning and memory impairments in mice lacking the M2 subtype of muscarinic receptor 

    Bainbridge, Natalie K.; Koselke, Lisa R.; Jeon, Jongrye; Wess, Jurgen; Crawley, Jacqueline N.; Wrenn, Craige C. (2007-05-31)
    The neurotransmitter acetylcholine is an important modulator of cognitive functions such as learning, memory, and attention. These functions of acetylcholine are mediated by its binding to five distinct subtypes of muscarinic ...
  • List Learning in Children 

    Rice, Anna L. (2009-04-28)
  • Looking for indicators of imminent cardiovascular collapse 

    Anklam, Ashley; Dumke, Breanna; Mueller, Dana; Verdick, Christopher; Woodard, Meredith; Hopkins, James; Devey, Jennifer; Buising, Charisse; Henderson, LaRhee; Wall, Piper (2007-05-31)
    Various indicators are used as predictors of lifesaving intervention requirements and mortality risk following severe hemorrhage. We examined hemorrhage and resuscitation data for sensitive and specific indications of ...
  • Malaria in Developing Countries : The Elusive Silent Killer 

    Adjei, Naomi; Yilma, Mariamawit (2010-04-28)
    Malaria is the most prevalent disease in Asia, Africa, Central and South America. Malaria is a serious, sometimes fatal disease caused by a parasite that is spread to humans through the bite of infected mosquitoes. The ...
  • Metallorganic Synthesis of A-Amino Acids 

    Secor, Ethan (2011-05-05)
    Amino acids are important biological compounds and useful chemical reagents in many chemistry applications. The ongoing investigation of the synthesis of α-amino acids was done via a metallorganic reaction of imines using ...
  • The Minimum Skew Rank of Simple Graphs to Strict Powers 

    Kerzner, Ethan; Tucker, Sarah (2010-05-10)
    Every simple graph can be represented by an adjacency matrix. The minimum skew rank of a graph is the smallest possible rank of all skew-symmetric matrices whose non-zero entries correspond to edges of the graph. Extensive ...
  • Mitigation Of Primate Crop Raiding In Gishwati Forest Reserve, Rwanda 

    Hess, Breanna; Hefferan, Danielle; Rupiper, Andrew (2013-04-25)
    Conservation efforts are sometimes undermined by human-animal conflicts near protected areas, such as wildlife raiding crops from local farms. Since 2007, crop raiding conflict has been observed between humans and non-human ...
  • Modeling Alzheimer’s disease in mice by selectively lesioning the cholinergic basal forebrain 

    Arter, Natalie; Wrenn, Craige C. (2007-06-01)
    One pathological feature of Alzheimer’s disease (AD) is the degeneration of the cholinergic basal forebrain (CBF). The importance of this degeneration in AD is suggested by the observation that the degree of CBF degeneration ...
  • Modified Shuttle Run Study of Three Different Cross-Training Shoes 

    Manske, Matia K.; James, Shaun D.; Klatt, Travis D.; Bumgarner, Michael R.; Fechner, Robert J. (2010-05-10)
    Background: Shuttle run-type exercises are used frequently in strength training programs. It is a movement that combines agility, strength and explosive movements as the person hops diagonally from point to point. The ...
  • Molecular Analysis of Isoflavonoid Genotoxicity 

    Walker, Greg; Verlinden, Nathan; Wrenn, Craige C. (2009-06-24)
    Overall objective of our research project is to analyze, at the molecular level, the genotoxic effects of genistein, the main isoflavonoid in soybeans. Due to their anti-oxidative properties, soy isoflavonoids have received ...
  • Molecular Analysis of the Effects of Resveratrol and Genistein on Signal Transduction in Cancer Cells 

    Hornick, Madeleine; Kang, Yutong (2011-04-20)
    The overall objective of our research project is to study the effects of Genistein and Resveratrol on cancer cell proliferation. Resveratrol, a stilbene found in high quantities in red grape skin, and Genistein, an ...