Search
Now showing items 1-5 of 5
-
"Characterizing reactivity of benzyl esters in sodium dodecyl sulfate micelles"
(2006-05-04)Purpose: To study the effect of changing structure of benzyl esters on its reactivity in sodium dodecyl sulfate micelles. Methods: Ester molecules with benzyl moiety were either purchased or synthesized. Alkyl groups of ... -
The Solubilization mechanism of benzyl esters in sodium dodecyl sulfate (SDS) micelles
(2007-06-01)Micelles are aggregates of surfactant molecules used to increase the solubility and bioavailability of poorly soluble pharmaceutical compounds. Past studies have suggested that a micelle is an oil droplet surrounded by a ... -
Assessing Resveratrol Phuronic F 127 Micelle Stability in the Presence of Plasma Proteins Using Fluorescence Resonance Energy Transfer (FRET)
(2010-04-21)Resveratrol (RES) is a polyphenolic compound with potential for chemopreventative and chemotherapeutic uses. However, exploration has been hindered by its short biologic half-life of ~6 minutes. Using polymeric micelles ... -
In Vitro Characterization of Resveratrol-Loaded Pluronic Micelles
(2010-04-21)Resveratrol (RES), a polyphenol has shown various biological activities but its use is hindered due to its hydrophobicity and short biological half-life. Biological studies require mega or frequent doses of RES to be ... -
Solubility of carbamazepine in aqueous solutions of sodium dodecyl sulfate
(2007-05-29)Carbamazepine (CZ) is a hydrophobic antiepileptic drug with a very low water solubility. It is important to identify means of improving the solubility of such drugs for better formulation and absorption. One approach to ...