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The Solubilization mechanism of benzyl esters in sodium dodecyl sulfate (SDS) micelles
Micelles are aggregates of surfactant molecules used to increase the solubility and bioavailability of poorly soluble pharmaceutical compounds. Past studies have suggested that a micelle is an oil droplet surrounded by a ...
Assessing Resveratrol Phuronic F 127 Micelle Stability in the Presence of Plasma Proteins Using Fluorescence Resonance Energy Transfer (FRET)
Resveratrol (RES) is a polyphenolic compound with potential for chemopreventative and chemotherapeutic uses. However, exploration has been hindered by its short biologic half-life of ~6 minutes. Using polymeric micelles ...
In Vitro Characterization of Resveratrol-Loaded Pluronic Micelles
Resveratrol (RES), a polyphenol has shown various biological activities but its use is hindered due to its hydrophobicity and short biological half-life. Biological studies require mega or frequent doses of RES to be ...
"Characterizing reactivity of benzyl esters in sodium dodecyl sulfate micelles"
Purpose: To study the effect of changing structure of benzyl esters on its reactivity in sodium dodecyl sulfate micelles. Methods: Ester molecules with benzyl moiety were either purchased or synthesized. Alkyl groups of ...
Solubility of carbamazepine in aqueous solutions of sodium dodecyl sulfate
Carbamazepine (CZ) is a hydrophobic antiepileptic drug with a very low water solubility. It is important to identify means of improving the solubility of such drugs for better formulation and absorption. One approach to ...