Now showing items 1-10 of 10
Monitoring microvascular blood flow during hemorrhage and resuscitation
Blood flow through the microvascular (arterioles, capillaries, venules) is critical to survival. Until recently, microvascular responses to cardiovascular events, such as hemorrhage and resuscitation, have been difficult ...
Inability to easily predict individual deaths in a hemorrhage and resuscitation model
While working on a hemorrhage with low-pressure stabilization protocol, we examined the possibility of identifying individual animals’ short term outcomes prior to occurrence using the hemorrhage patterns of variables ...
Comparing venous to arterial base deficit during hemorrhage and resuscitation
Arterial base deficit is used in assessing trauma patient oxygen debt, life saving intervention requirements, resuscitation adequacy, and mortality risk. Venous blood samples are simpler and less painful to obtain than ...
Gross tissue appearances following hemorrhage, low-pressure stabilization, and resuscitation
In a severe prolonged hemorrhage and resuscitation protocol, when do gross abnormalities become apparent? Hypothesis: Gross tissue abnormalities will be more obvious in those animals that survive longer. Methods: 8 ...
"Assessing trauma patient risk using non-invasive indicators"
Non-invasive indicators of a trauma patient's risk of cardiovascular collapse are needed. Exhaled alveolar air (end-tidal air) and skin surface are available non-invasively and have physiologic reasons to relate to trauma ...
"Chest skin and sublingual PCO2 during hemorrhage"
Base deficit is an indicator for degree of metablic insult/oxygen debt from hemorrhage and is moratlity risk related in trauma patients. We investigated the use of less invasively available skin and sublingual partial ...
"Ion and albumin influence on measurement of metabolic debt"
Alterations in Na+, Cl-, and albumin, if present and not accounted for, may lead one to false conclusions concerning perfusion status as indicated by base excess (BEtotal).
"Sweat may impair skin carbon dioxide (PCO2) dependent discrimination in trauma patients"
Assessing internal bleeding from trauma is difficult. Non-invasive discriminationrs between the physiologic changes of exercise (or excitement) and injury could be useful, especially at locations with limited access to ...
"Issues with hypotensive stabilization following hemorrhage"
We are investigating pharmacologic interruption of angiotensin II production (enalaprilat) combined with either 7.8% hypertonic saline dextran (HSD) or a hemoglobin based oxygen carrier (HBOC, Oxyglobin) as methods to ...
Looking for indicators of imminent cardiovascular collapse
Various indicators are used as predictors of lifesaving intervention requirements and mortality risk following severe hemorrhage. We examined hemorrhage and resuscitation data for sensitive and specific indications of ...