Browsing by Author "Moeller, Bryant M."
Now showing items 1-2 of 2
-
HPLC with Fluorometric Detection of Brain Catecholamines in a Pharmacodynamic Study Between Two Popular Antidepressants
(2010-04-21)Drug-drug interactions are a serious concern in US health care today, accounting for over 100,000 deaths annually. Bupropion (Wellbutrin®) is a well-established monocyclic antidepressant that is also used in the treatment ... -
HPLC-UV Analysis of Bupropion and Hydroxybupropion : Application to In Vivo Pharmacokinetic Drug-Drug Interaction Studies Between Bupropion and Potent CYP2B6 Inhibitors
(2010-04-28)Bupropion is a popular antidepressant that is also prescribed in the management of smoking cessation. In humans, bupropion is predominantly metabolized to its active metabolite hydroxybupropion by CYP2B6. Inhibitors of ...