Effects of Marek's Disease Herpesvirus and Turkey Herpesvirus Upon Immunity to Eimeria Acervulina in Young Chickens

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dc.contributor.author Herr, Marvin Leroy
dc.date.accessioned 2009-04-24T16:21:03Z
dc.date.available 2009-04-24T16:21:03Z
dc.date.issued 1975-01
dc.identifier.other 1975 .H434
dc.identifier.uri http://hdl.handle.net/2092/917
dc.description 42 leaves. Advisor: Dr. Rodney A. Rogers en_US
dc.description.abstract The problem. Concurrent infections with Marek's disease (MD) and coccidiosis in chicken flocks have perplexed investigators for years. Infection with MD herpesvirus has been shown to inhibit immunity of chicks to three species of Eimeria. Herpesvirus from turkeys (HVT) is used commercially as a vaccine against MD. This investigation studied the response to primary and secondary exposures to E. acervulina oocysts in young chicks infected with either MDHV or HVT. Procedure. Groups of chickens were inoculated with either MDHV or HVT. These chicks received a primary immunizing series of inoculations with E. acervulina oocysts. Individual chick weights were recorded during this period. The chicks were subsequently challenged with a massive dose of E. acervulina oocysts. Following challenge chicks were monitored for weight gain or loss and for the number of oocysts passed in the feces. Five to seven days following challenge all chicks were killed and autopsied to evaluate for E. acervulina and MD lesions. Data from these chicks were compared to data from control chicks which received oocysts but no virus. Findings. Weight gains, oocyst recovery data, and autopsy observations for experimental and control chicks are equivalent. Conclusions. Neither MDHV nor HVT had any effect upon the immune response of young chicks to E. acervulina. Vaccination of chicks with HVT did not jeopardize development of resistance to E. acervulina. Recommendations. Further studies with other strains of MDHV or with other species of Eimeria would be helpful in better understanding the relationship of MD and coccidiosis. en_US
dc.language.iso en_US en_US
dc.publisher Drake University en_US
dc.relation.ispartofseries Drake University, School of Graduate Studies;1975
dc.subject Marek's disease en_US
dc.subject Coccidiosis in animals en_US
dc.subject Herpesvirus diseases en_US
dc.subject Chickens--Diseases en_US
dc.title Effects of Marek's Disease Herpesvirus and Turkey Herpesvirus Upon Immunity to Eimeria Acervulina in Young Chickens en_US
dc.type Thesis en_US

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