Evaluation of Transmissible Gastroenteritis and Porcine Respiratory Coronavirus Immunologic Interaction in Seronegative Pregnant Gilts

DSpace/Manakin Repository

Show simple item record

dc.contributor.author Allen, Michelle Horstman
dc.date.accessioned 2006-11-30T14:16:00Z
dc.date.available 2006-11-30T14:16:00Z
dc.date.issued 1994-07
dc.identifier.other 1994 .H788
dc.identifier.uri http://hdl.handle.net/2092/467
dc.description 19 leaves. Advisor: Mark Welter en
dc.description.abstract The primary objective of this study was to determine if Porcine Respiratory Coronavirus (PRCV) sensitized gilts responded to intranmuscular (IM) vaccination with Transmissible Gastroenteritis Virus (TGEV) in a similar fashion as gilts sensitized to TGEV alone. It was demonstrated that pregnant gilts sensitized to PRCV, prior to TGEV vaccination, do not produce significantly higher TGEV serum neutralizing antibody titers when compared with gilts sensitized to either PRCV or TGEV alone, Anti-TOEV IgG and IgA levels were assayed for in post-farrow milks from all gilt groups. Only IgG was detected which indicated a lack of mucosal priming. The second objective of this study was to determine if animals, which have recovered from a TGEV infection, can be infected with PRCV. TGEV antibodies circulating in these exposed piglets prevented PRCV infection as demonstrated by the absence of PRCV shedding during the post-challenge period. It was found that these piglets had an eight-fold boost in TGEV serum neutralizing antibody titers 21-days post PRCV challenge. Piglets that had not been exposed to TGEV significantly shed virus during this same post-challenge period and exhibited a three-fold boost in TGEV neutralizing antibody titer. Piglets that had suckled TGEV immune dams were also, for the most part, protected from PRCV shedding but exhibited no boost in TGEV serum neutralizing antibody titer. en
dc.format.extent 1047774 bytes
dc.format.mimetype application/pdf
dc.language.iso en_US
dc.publisher Drake University en
dc.relation.ispartofseries Drake University Theses, College of Arts and Sciences;1994
dc.subject Transmissible gastroenteritis of swine--Evaluation en
dc.subject Sows--Pregnancy--Immunology en
dc.subject Coronavirus infections--Evaluation en
dc.title Evaluation of Transmissible Gastroenteritis and Porcine Respiratory Coronavirus Immunologic Interaction in Seronegative Pregnant Gilts en
dc.type Thesis en


Files in this item

This item appears in the following Collection(s)

Show simple item record

Search DSpace


Advanced Search

Browse

My Account