"Gastroesophageal reflux disease"

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dc.contributor.author Wall, Geoffrey C.
dc.contributor.author Jacoby, Henry I.
dc.date.accessioned 2006-08-30T19:24:31Z
dc.date.available 2006-08-30T19:24:31Z
dc.date.issued 2002
dc.identifier.citation American Journal of Pharmaceutical Education, Volume 66, Issue 2, 2002, Pages 148-152 en
dc.identifier.issn 0002-9459
dc.identifier.uri http://hdl.handle.net/2092/404
dc.description Geoffrey C. Wall is an Associate Professor of Pharmacy Practice in the College of Pharmacy and Health Sciences. He can be contacted at geoff.wall@drake.edu en
dc.description.abstract PROLOGUE: Gastroesophageal reflux disease (GERD) is a pathologic condition of injury to the esophagus caused by regurgitation of gastric or gastroduodenal contents into the lumen of the esophagus. Histopathology of the esophageal mucosa may or may not be present. Gastroesophageal reflux of acid and gastric contents often causes a condition commonly referred to as heartburn. This is characterized as a retro-sternal burning sensation that radiates to the throat and interscapular region. It may be confused, even in the emergency room, with anginal pain or the onset of myocardial infarction; therefore its rapid diagnosis is important. In many patients GERD should be considered a chronic and lifelong illness and maintenance therapy is often needed. Repeated exposure of the esophagus to stomach contents leads to esophagitis. In severe cases, this can actually erode esophageal tissue (erosive esophagitis). In the last five to seven years several new treatment options for GERD have become available. These include antise-cretory agents such as the proton pump inhibitors, and new surgical techniques that have improved Nissen fundoplication safety and efficacy rates(3-4). Clinicians caring for patients with this common disorder need to understand the pathology behind GERD, its common (and uncommon) clinical manifestations, and current treatment options as recommended by the American College of Gastroenterology. en
dc.format.extent 466652 bytes
dc.format.mimetype application/pdf
dc.language.iso en_US
dc.publisher American Association of Colleges of Pharmacy en
dc.subject Gastroesophageal reflux. en
dc.subject Gastroesophageal reflux--Diagnosis. en
dc.subject Gastroesophageal reflux--Diet therapy. en
dc.subject Gastroesophageal reflux--Treatment en
dc.subject Esophagus--Diseases. en
dc.subject Esophageal sphincter. en
dc.subject Heartburn. en
dc.title "Gastroesophageal reflux disease" en
dc.type Article en


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  • Pharmacy Practice [7]
    Publications and research submitted by the faculty members of the Department of Pharmacy Practice.

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