"Gastroesophageal reflux disease"
Wall, Geoffrey C.
Jacoby, Henry I.
MetadataShow full item record
SubjectGastroesophageal reflux.; Gastroesophageal reflux--Diagnosis.; Gastroesophageal reflux--Diet therapy.; Gastroesophageal reflux--Treatment; Esophagus--Diseases.; Esophageal sphincter.; Heartburn.
PROLOGUE: Gastroesophageal reflux disease (GERD) is a pathologic condition of injury to the esophagus caused by regurgitation of gastric or gastroduodenal contents into the lumen of the esophagus. Histopathology of the esophageal mucosa may or may not be present. Gastroesophageal reflux of acid and gastric contents often causes a condition commonly referred to as heartburn. This is characterized as a retro-sternal burning sensation that radiates to the throat and interscapular region. It may be confused, even in the emergency room, with anginal pain or the onset of myocardial infarction; therefore its rapid diagnosis is important. In many patients GERD should be considered a chronic and lifelong illness and maintenance therapy is often needed. Repeated exposure of the esophagus to stomach contents leads to esophagitis. In severe cases, this can actually erode esophageal tissue (erosive esophagitis). In the last five to seven years several new treatment options for GERD have become available. These include antise-cretory agents such as the proton pump inhibitors, and new surgical techniques that have improved Nissen fundoplication safety and efficacy rates(3-4). Clinicians caring for patients with this common disorder need to understand the pathology behind GERD, its common (and uncommon) clinical manifestations, and current treatment options as recommended by the American College of Gastroenterology.
Geoffrey C. Wall is an Associate Professor of Pharmacy Practice in the College of Pharmacy and Health Sciences. He can be contacted at firstname.lastname@example.org
Showing items related by title, author, creator and subject.
Effects of Marek's Disease Herpesvirus and Turkey Herpesvirus Upon Immunity to Eimeria Acervulina in Young Chickens Herr, Marvin Leroy (Drake University, 1975-01)The problem. Concurrent infections with Marek's disease (MD) and coccidiosis in chicken flocks have perplexed investigators for years. Infection with MD herpesvirus has been shown to inhibit immunity of chicks to ...
Dirth, Deidra; Meggison, Jordan; Pope, Elizabeth; Woodland, Heidi (2009-06-24)Autoimmune diseases are the fourth most common type of chronic illness yet the medical causes of the diseases remain largely unknown. Individuals who are diagnosed with autoimmune diseases often face many psychosocial ...
Rajewski, Alex (2010-04-28)The Geminiviridae are a family of single-stranded DNA plant viruses that cause severe crop destruction especially in the tropics. Much of the research into geminivirus replication and resistance is conducted in model ...