"Issues with hypotensive stabilization following hemorrhage"
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We are investigating pharmacologic interruption of angiotensin II production (enalaprilat) combined with either 7.8% hypertonic saline dextran (HSD) or a hemoglobin based oxygen carrier (HBOC, Oxyglobin) as methods to improve blook dlows with minimal IV fluid during intentional, severe post-hemorrhage hypotension.
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Heck, Amber; Mueller, Dana; Woodard, Meredith; Lewis, Trisha; Waszgis, Michaela; Theisen-Toupal, Jesse; Sanders, Rachel; Matlack, Angela; Buising, Charisse; Henderson, LaRhee; Hopkins, James; Devey, Jennifer; Smoot, Dustin; Wall, Piper (2006-06-07)Alterations in Na+, Cl-, and albumin, if present and not accounted for, may lead one to false conclusions concerning perfusion status as indicated by base excess (BEtotal).
Hukee, Luke; Paul, Butler; Singh, Sid; Prakash, Shawn; Lewis, Trisha; Waszgis, Michaela; Heck, Amber; Bellani, Denisa; Sanders, Rachel; Matlack, Angela; Theisen-Toupal, Jesse; Hopkins, James; Henderson, LaRhee; Smoot, Dustin; Buising, Charisse; Wall, Piper (2006-06-05)Base deficit is an indicator for degree of metablic insult/oxygen debt from hemorrhage and is moratlity risk related in trauma patients. We investigated the use of less invasively available skin and sublingual partial ...
Anklam, Ashley; Dumke, Breanna; Mueller, Dana; Verdick, Christopher; Woodard, Meredith; Hopkins, James; Devey, Jennifer; Buising, Charisse; Henderson, LaRhee; Wall, Piper (2007-05-31)Various indicators are used as predictors of lifesaving intervention requirements and mortality risk following severe hemorrhage. We examined hemorrhage and resuscitation data for sensitive and specific indications of ...