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dc.contributor.authorBrozik, Melissa
dc.contributor.authorFrazee, Erin
dc.contributor.authorBohorquez, Maria
dc.descriptionMelissa Brozik and Erin Frazee are students at Drake University. Maria Bohorquez is Associate Professor of Chemistry in the College of Arts and Sciences at Drake. She can be contacted at maria.bohorquez@drake.eduen
dc.description.abstractMolecular interactions between indole derivatives and 1,2-di-oleoyl-sn-glycero-3-phosphocholine (DOPC) were studied using a Nima Langmuir-Blodgett (LB) trough. A 0.25 M phosphate buffer sub-phase was used with a physiological pH range of 7.31-7.48. The air-phosphate buffer interface was examined at room temperature. Constant ionic strength was maintained by 0.100 M potassium chloride (KCl). Two different indole derivatives were used, indole and tryptophan, in concentrations of 3.0 uM and 5.0 uM. It is evident when examining the isotherms that the DOPC monolayer is expanded in the presence of indole derivatives, as the area per molecule was increased by 0.02nm2/molecule.en
dc.description.sponsorshipDrake University, College of Arts and Sciences, Department of Chemistry, and NSF Grant 0311325.en
dc.format.extent852888 bytes
dc.relation.ispartofseriesDUCURS 2005;18
dc.subjectAmino acidsen
dc.title"Indole derivatives interact with DOPC in Langmuir monolayers"en

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    Poster sessions and presentation from the Drake University Conference on Undergraduate Research in the Sciences held each April at Olmsted Center on the Drake campus.

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