Abstract:
Phase transfer catalyzed oxidation of cholesterol and related compounds with sodium hypochlorite in ethyl acetate resulted in good to excellent yields of oxidized products. These reactions are mild, eficient, and safe. The experimental procedures and work-ups are very convenient. A representative sample of our oxidation results using primary, secondary, and benzylic alcohols as well as some of our recent results on selective oxidation of alcohols using this system will be presented.
