Molecular Analysis of the Effects of Resveratrol and Genistein on Signal Transduction in Cancer Cells

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dc.contributor.author Hornick, Madeleine
dc.contributor.author Kang, Yutong
dc.date.accessioned 2011-04-20T19:17:54Z
dc.date.available 2011-04-20T19:17:54Z
dc.date.issued 2011-04-20T19:17:54Z
dc.identifier.uri http://hdl.handle.net/2092/1573
dc.description Mentors: Dr. Deepa Rao and Dr. Pramod Mahajan en_US
dc.description.abstract The overall objective of our research project is to study the effects of Genistein and Resveratrol on cancer cell proliferation. Resveratrol, a stilbene found in high quantities in red grape skin, and Genistein, an isoprenoid found in soy, are both available in supplement form and have exhibited antioxidative properties. Recent studies have suggested Genistein and Resveratrol may inhibit growth of certain types of cancer cells in culture, and that diets with higher levels of these two compounds have shown lower incidence of certain types of cancers and inflammatory disorders. However, the precise mechanisms of their antiproliferative effects only on certain types of cancer cells remain poorly defined. Our project focuses on studying the anti-proliferative effects of Resveratrol and Genistein on signal transduction pathways in two human breast cancer cell lines and one human ovarian cancer cell line in culture. Specifically, this poster presents results examining the role of phosphorylation of two signal transduction enzymes, PDK1 and Akt1. en_US
dc.description.sponsorship Drake University, College of Pharmacy & Health Sciences en_US
dc.language.iso en_US en_US
dc.relation.ispartofseries DUCURS 2011;16
dc.subject Resveratrol--Analysis en_US
dc.subject Genistein--Analysis en_US
dc.subject Cancer cells en_US
dc.title Molecular Analysis of the Effects of Resveratrol and Genistein on Signal Transduction in Cancer Cells en_US
dc.type Presentation en_US


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  • DUCURS [196]
    Poster sessions and presentation from the Drake University Conference on Undergraduate Research in the Sciences held each April at Olmsted Center on the Drake campus.

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